Modified fixture list following withdrawal of Perth TC
| Date | Home Team | Away team |
| Week 1 | Aberfeldy | Bridge of Earn |
| 14/07/2022 | Coupar Agus | Bye |
| Scone | Dunning 2 | |
| Week 2 | Coupar Agus | Aberfeldy |
| 21/07/2022 | Bridge of Earn | Dunning 2 |
| Bye | Scone | |
| Week 3 | Bye | Aberfeldy |
| 28/07/2022 | Dunning 2 | Coupar Angus |
| Bridge of Earn | Scone | |
| Week 4 | Aberfeldy | Dunning 2 |
| 04/08/2022 | Scone | Coupar Angus |
| Bridge of Earn | Bye | |
| Week 5 | Scone | Aberfeldy |
| 11/08/2022 | Dunning 2 | Bye |
| Coupar Agus | Bridge of Earn | |
| Week 6 | Bridge of Earn | Aberfeldy |
| 18/08/2022 | Bye | Coupar Angus |
| Dunning 2 | Scone | |
| Week 7 | Aberfeldy | Coupar Angus |
| 25/08/2022 | Dunning 2 | Bridge of Earn |
| Scone | Bye | |
| Week 8 | Aberfeldy | Bye |
| 01/09/2022 | Coupar Agus | Dunning 2 |
| Scone | Bridge of Earn | |
| Week 9 | Dunning 2 | Aberfeldy |
| 08/09/2022 | Coupar Agus | Scone |
| Bye | Bridge of Earn | |
| Week 10 | Abereldy | Scone |
| 15/09/2022 | Bye | Dunning 2 |
| Bridge of Earn | Coupar Angus |